Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29157180 | 0.94 | SLC6A2 (0.38) | SLC6A2SLC6A3TSHRFFAR1ABHD6 | |
| SCHEMBL29157190 | 0.80 | GAA (0.40) | — | |
| SCHEMBL4310339 | 0.78 | TSHR (0.45) | TSHRFFAR1GRIN2B | |
| SCHEMBL31716318 | 0.74 | HTT (0.36) | TSHRPDCD1CD274 | |
| SCHEMBL28699610 | 0.73 | TSHR (0.43) | TSHRFFAR1GRIN2B | |
| SCHEMBL26365753 | 0.72 | TSHR (0.33) | TSHR | |
| SCHEMBL32674217 | 0.69 | TSHR (0.37) | TSHR | |
| SCHEMBL4317544 | 0.69 | TSHR (0.37) | TSHR | |
| SCHEMBL28885401 | 0.69 | KDM1A (0.41) | TSHRPDCD1CD274MAPT | |
| SCHEMBL26134036 | 0.68 | ALDH1A1 (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551037-A | Compounds as succinate dehydrogenase inhibitors and uses thereof | 华东理工大学 | 2024-02-13 | — | — | CN | disclosed |