⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27265120 | 0.76 | MEN1 (0.34) | — | |
| SCHEMBL28631775 | 0.72 | SLC1A2 (0.31) | — | |
| Trifluoroacetic Acid SCHEMBL29158076 | 0.72 | FUCA1 (0.32) | — | |
| SCHEMBL6568314 | 0.70 | — | — | |
| SCHEMBL6568149 | 0.70 | CHRNB2 (0.30) | — | |
| SCHEMBL15995376 | 0.70 | CYP19A1 (0.39) | — | |
| SCHEMBL6566931 | 0.69 | — | — | |
| SCHEMBL21598160 | 0.68 | CHRNA7 (0.41) | — | |
| SCHEMBL6567291 | 0.67 | — | — | |
| SCHEMBL27976432 | 0.66 | CYP19A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062814-A | Compounds that rapidly accelerate fibrosarcoma protein degradation and related methods of use | 阿维纳斯运营公司 | 2023-11-14 | — | — | CN | disclosed |