Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29049309 | 1.00 | FFAR1 (0.65) | FFAR1GLACRBNDDB1HTT | |
| SCHEMBL9017825 | 0.85 | FFAR1 (0.50) | FFAR1GLACRBNDDB1KMT2A | |
| SCHEMBL11627271 | 0.83 | GLA (0.64) | FFAR1GLACRBNDDB1HTT | |
| SCHEMBL11270285 | 0.83 | GLA (0.60) | FFAR1GLACRBNDDB1HTT | |
| SCHEMBL31139945 | 0.83 | GLA (0.60) | FFAR1GLACRBNDDB1HTT | |
| SCHEMBL5767796 | 0.83 | GLA (0.60) | FFAR1GLACRBNDDB1HTT | |
| SCHEMBL7268381 | 0.82 | CRBN (0.70) | FFAR1GLACRBNDDB1HTT | |
| SCHEMBL29049422 | 0.81 | FFAR1 (0.56) | FFAR1GLACRBNDDB1KMT2A | |
| SCHEMBL30526504 | 0.81 | FFAR1 (0.56) | FFAR1GLACRBNDDB1KMT2A | |
| SCHEMBL11629119 | 0.79 | GLA (0.59) | FFAR1GLACRBNDDB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551018-B | (R) -1-benzyl-3- (4-chlorobenzyl) pyrrolidine-2, 5-dione and preparation method and application thereof | 宁夏医科大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-117551018-A | (R) -1-benzyl-3- (4-chlorophenyl) pyrrolidine-2, 5-dione and preparation method and application thereof | 宁夏医科大学 | 2024-02-13 | — | — | CN | disclosed |