Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31139945 | 0.83 | GLA (0.60) | GLAFFAR1CRBNDDB1HTT | |
| SCHEMBL29158181 | 0.83 | FFAR1 (0.65) | GLAFFAR1CRBNDDB1HTT | |
| SCHEMBL5767796 | 0.83 | GLA (0.60) | GLAFFAR1CRBNDDB1HTT | |
| SCHEMBL11627271 | 0.83 | GLA (0.64) | GLAFFAR1CRBNDDB1HTT | |
| SCHEMBL29049309 | 0.83 | FFAR1 (0.65) | GLAFFAR1CRBNDDB1HTT | |
| SCHEMBL7268381 | 0.82 | CRBN (0.70) | GLAFFAR1CRBNDDB1HTT | |
| SCHEMBL28411469 | 0.79 | GLA (0.56) | GLAFFAR1CRBNDDB1HTT | |
| SCHEMBL11629119 | 0.79 | GLA (0.59) | GLAFFAR1CRBNDDB1HTT | |
| SCHEMBL4138166 | 0.79 | GAA (0.41) | GAAPOLBGSK3BBACE1ALDH1A1 | |
| Bicarbonate SCHEMBL29264497 | 0.78 | CRBN (0.64) | GLAFFAR1CRBNDDB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066484-A1 | Process for the preparation of N-benzyl-substituted imides | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1982-12-08 | — | — | EP | disclosed |