Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | EIF4E | P06730 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158753 | 0.90 | EIF4E (0.44) | TRPV1EIF4EPOLBMEN1KMT2A | |
| SCHEMBL29158589 | 0.89 | EIF4E (0.45) | TRPV1EIF4EPOLBMEN1KMT2A | |
| SCHEMBL29158612 | 0.89 | EIF4E (0.43) | TRPV1EIF4EHDAC4HDAC6POLB | |
| SCHEMBL30106286 | 0.88 | EIF4E (0.41) | TRPV1EIF4EPOLBMEN1KMT2A | |
| SCHEMBL29158660 | 0.88 | EIF4E (0.42) | TRPV1EIF4EPOLBMEN1KMT2A | |
| SCHEMBL30106335 | 0.87 | GAA (0.43) | TRPV1EIF4EPOLBMEN1KMT2A | |
| SCHEMBL29158703 | 0.87 | EIF4E (0.43) | TRPV1EIF4EPOLBMEN1KMT2A | |
| SCHEMBL30106366 | 0.86 | POLB (0.53) | EIF4EPOLBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL29158684 | 0.86 | POLB (0.44) | EIF4EHDAC4POLBSMN1; SMN2LMNA | |
| SCHEMBL29158630 | 0.86 | HPGD (0.51) | POLBABCG2MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |