Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | EIF4E | P06730 | 3/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MTTP | P55157 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189055 | 0.97 | POLB (0.50) | POLBEIF4EGSK3BTHRBLMNA | |
| SCHEMBL29158665 | 0.95 | GSK3B (0.52) | POLBEIF4EGSK3BTHRBLMNA | |
| SCHEMBL29158630 | 0.93 | HPGD (0.51) | POLBGSK3BTHRBALDH1A1GAA | |
| SCHEMBL29158715 | 0.91 | THRB (0.56) | POLBEIF4EGSK3BTHRBLMNA | |
| SCHEMBL30740880 | 0.91 | THRB (0.56) | POLBEIF4EGSK3BTHRBLMNA | |
| SCHEMBL29158684 | 0.89 | POLB (0.44) | POLBEIF4EGSK3BLMNAALDH1A1 | |
| SCHEMBL29158589 | 0.88 | EIF4E (0.45) | POLBEIF4EGSK3BLMNAALDH1A1 | |
| SCHEMBL29158755 | 0.88 | RAB9A (0.43) | POLBEIF4ELMNAALDH1A1GAA | |
| SCHEMBL29158753 | 0.87 | EIF4E (0.44) | POLBEIF4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29158587 | 0.86 | TRPV1 (0.46) | POLBEIF4ELMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255764-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | disclosed |