SCHEMBL29158751

SCHEMBL29158751

CCOC(=O)c1nc(-c2ccc(C(F)(F)F)cc2)oc1-c1ccc(C(C)=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TARBP2 Q15633 6/20 0.51
MAPT P10636 3/20 0.51
KDM4E B2RXH2 2/20 0.51
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
HSP90AA1 P07900 1/20 0.51
CRHBP P24387 1/20 0.51
CRHR2 Q13324 1/20 0.51
PDCD4 Q53EL6 1/20 0.48
IKBKB O14920 2/20 0.48
PPARD Q03181 2/20 0.46
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
HSD17B10 Q99714 1/20 0.45
ADORA3 P0DMS8 2/20 0.43
POLB P06746 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PTPN1 P18031 1/20 0.42
MLYCD O95822 1/20 0.42
PPARG P37231 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29158666 0.90 TARBP2 (0.54) TARBP2MAPTKDM4EKMT2AMEN1
SCHEMBL29158606 0.89 TARBP2 (0.63) TARBP2MAPTKDM4EKMT2AMEN1
SCHEMBL6365824 0.89 TARBP2 (0.53) TARBP2MAPTKDM4EKMT2AMEN1
SCHEMBL29158800 0.89 TARBP2 (0.50) TARBP2MAPTKDM4EKMT2AMEN1
SCHEMBL7701393 0.88 TARBP2 (0.52) TARBP2MAPTKDM4EKMT2AMEN1
SCHEMBL6373442 0.87 TARBP2 (0.52) TARBP2MAPTKDM4EKMT2AMEN1
SCHEMBL29158788 0.87 TARBP2 (0.66) TARBP2MAPTKDM4EKMT2AMEN1
SCHEMBL29158623 0.86 TARBP2 (0.48) TARBP2MAPTKDM4EKMT2AMEN1
SCHEMBL7693858 0.86 MAPT (0.53) TARBP2MAPTKDM4EKMT2AMEN1
SCHEMBL29158582 0.86 TARBP2 (0.50) TARBP2MAPTKDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117396465-A Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same 阿斯克里斯有限公司 2024-01-12 CN claimed
CN-117396465-A Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same 阿斯克里斯有限公司 2024-01-12 CN disclosed