Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 6/20 | 0.52 |
| ▸ | IKBKB | O14920 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158666 | 0.91 | TARBP2 (0.54) | TARBP2IKBKBKDM4EKMT2AMAPT | |
| SCHEMBL29158606 | 0.90 | TARBP2 (0.63) | TARBP2IKBKBKDM4EKMT2AMAPT | |
| SCHEMBL6365824 | 0.90 | TARBP2 (0.53) | TARBP2IKBKBKDM4EKMT2AMAPT | |
| SCHEMBL7694080 | 0.90 | IKBKB (0.55) | TARBP2IKBKBKDM4EKMT2AMAPT | |
| SCHEMBL29158706 | 0.89 | TARBP2 (0.51) | TARBP2IKBKBKDM4EKMT2AMAPT | |
| SCHEMBL29158788 | 0.88 | TARBP2 (0.66) | TARBP2IKBKBKDM4EKMT2AMAPT | |
| SCHEMBL29158751 | 0.88 | TARBP2 (0.51) | TARBP2IKBKBKDM4EKMT2AMAPT | |
| SCHEMBL29158582 | 0.87 | TARBP2 (0.50) | TARBP2IKBKBKDM4EKMT2AMAPT | |
| SCHEMBL7693955 | 0.87 | KDM4E (0.52) | TARBP2IKBKBKDM4EKMT2AMAPT | |
| SCHEMBL7701292 | 0.86 | TARBP2 (0.67) | TARBP2IKBKBKDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |