Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29159250 | 0.88 | GRIA2 (0.56) | GRIA2HDAC1HDAC6GRIA1GRIA3 | |
| SCHEMBL30707941 | 0.79 | HDAC1 (0.53) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL21643754 | 0.74 | HDAC1 (0.87) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL22823720 | 0.73 | GRIA2 (1.00) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL32682813 | 0.73 | GRIA2 (1.00) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL5359084 | 0.72 | GRIA2 (0.73) | GRIA2GRIA1GRIA3GRIA4 | |
| SCHEMBL19260229 | 0.72 | HDAC1 (1.00) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL28633676 | 0.72 | HDAC1 (0.95) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL20548017 | 0.71 | HDAC6 (0.87) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL21643770 | 0.71 | HDAC1 (0.70) | HDAC1HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285484-B | Benzothiadiazine 1, 1-dioxide compounds inhibiting HDAC6 enzyme, preparation method and application thereof | Shanghai Pharmaceutical Industry Research Institute Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-117285484-A | Benzothiadiazine 1, 1-dioxide compounds inhibiting HDAC6 enzyme, preparation method and application thereof | 上海医药工业研究院有限公司 | 2023-12-26 | — | — | CN | disclosed |