Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.62 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.50 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL28833029 | 0.88 | SLC7A5 (0.64) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| Leucine SCHEMBL9068238 | 0.86 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| Naphthalene SCHEMBL8050413 | 0.84 | SLC7A5 (0.69) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| Naphthalene SCHEMBL8050416 | 0.84 | SLC7A5 (0.69) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| Leucine SCHEMBL21634011 | 0.83 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| Leucine SCHEMBL4551207 | 0.82 | SLC7A5 (0.67) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| Leucine SCHEMBL21141614 | 0.82 | SLC7A5 (0.67) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| Leucine SCHEMBL3362636 | 0.81 | SLC7A5 (0.95) | SLC7A5SLC1A3SLC1A2RNPEPSLC1A1 | |
| Leucine SCHEMBL3362642 | 0.81 | SLC7A5 (0.95) | SLC7A5SLC1A3SLC1A2RNPEPSLC1A1 | |
| Anthraquinone SCHEMBL27983864 | 0.81 | SLC7A5 (0.64) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603042-A | Preparation method and application of ketoleucine salt derivative | 河北天成药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |