Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CES2 | O00748 | 4/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.52 |
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL29218027 | 0.98 | DGKA (0.55) | DGKAMAPTMAPK1LMNACES2 | |
| SCHEMBL8470275 | 0.96 | DGKA (0.61) | DGKAMAPTMAPK1LMNACES2 | |
| SCHEMBL10972306 | 0.96 | DGKA (0.61) | DGKAMAPTMAPK1LMNACES2 | |
| SCHEMBL27963347 | 0.96 | DGKA (0.61) | DGKAMAPTMAPK1LMNACES2 | |
| SCHEMBL28410534 | 0.96 | DGKA (0.61) | DGKAMAPTMAPK1LMNACES2 | |
| SCHEMBL9491539 | 0.96 | DGKA (0.61) | DGKAMAPTMAPK1LMNACES2 | |
| SCHEMBL30668427 | 0.96 | DGKA (0.61) | DGKAMAPTMAPK1LMNACES2 | |
| SCHEMBL7221660 | 0.96 | DGKA (0.61) | DGKAMAPTMAPK1LMNACES2 | |
| SCHEMBL28084305 | 0.96 | DGKA (0.61) | DGKAMAPTMAPK1LMNACES2 | |
| SCHEMBL27566336 | 0.96 | DGKA (0.61) | DGKAMAPTMAPK1LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603656-A | Oleophobic biochar/paraffin composite phase-change material and preparation method thereof | 华北电力大学（保定） | 2024-02-27 | — | — | CN | disclosed |