Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28095892 | 0.89 | P2RY12 (0.45) | P2RY12TBK1PRKDCPIK3CAMEN1 | |
| SCHEMBL29160479 | 0.85 | TTR (0.48) | TTRKMOAKR1B1TBK1PRKDC | |
| SCHEMBL31035311 | 0.83 | PRKDC (0.61) | P2RY12PRKDCKMT2AKDM4EALDH1A1 | |
| SCHEMBL29160429 | 0.76 | PRKDC (0.65) | PRKDCPIK3CAKDM4EALDH1A1TP53 | |
| SCHEMBL7315291 | 0.76 | PRKDC (0.59) | P2RY12AKR1B1PRKDCMEN1KMT2A | |
| SCHEMBL30768013 | 0.76 | PIK3CB (0.48) | PIK3CA | |
| SCHEMBL30768016 | 0.72 | PIK3CB (0.43) | PIK3CAHSD17B10 | |
| SCHEMBL68189 | 0.72 | TTR (0.83) | TTRAKR1B1TBK1MEN1KMT2A | |
| SCHEMBL11439145 | 0.72 | TTR (0.59) | TTRAKR1B1MEN1KMT2AKDM4E | |
| SCHEMBL28095893 | 0.72 | P2RY12 (0.44) | P2RY12TBK1PRKDCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117615763-A | Phosphoinositide 3 kinase beta inhibitor, composition and preparation method thereof | 健道生物医药有限公司 | 2024-02-27 | — | — | CN | disclosed |