Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.71 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340654 | 0.93 | ALDH1A1 (0.69) | PRMT1TAAR1HSD17B10ALDH1A1MAPT | |
| SCHEMBL16187956 | 0.91 | ALDH1A1 (0.63) | PRMT1TAAR1HSD17B10ALDH1A1MAPT | |
| SCHEMBL412302 | 0.88 | ALDH1A1 (0.79) | PRMT1TAAR1HSD17B10ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3517769 | 0.86 | ALDH1A1 (0.77) | PRMT1TAAR1HSD17B10ALDH1A1MAPT | |
| SCHEMBL11119146 | 0.84 | TBXA2R (0.77) | PRMT1TAAR1HSD17B10ALDH1A1MAPT | |
| SCHEMBL10452817 | 0.84 | ALDH1A1 (0.55) | PRMT1TAAR1HSD17B10ALDH1A1MAPT | |
| SCHEMBL5925404 | 0.84 | ALDH1A1 (0.84) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL1287281 | 0.83 | PRMT1 (0.83) | PRMT1TAAR1HSD17B10ALDH1A1MAPT | |
| SCHEMBL625181 | 0.83 | ALDH1A1 (0.84) | PRMT1TAAR1HSD17B10ALDH1A1MAPT | |
| SCHEMBL3915476 | 0.83 | PRMT1 (0.71) | PRMT1TAAR1HSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222160-A2 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | Pharmaxis Ltd. (AU) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009066152-A2 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD. (US) | 2009-05-28 | — | — | WO | disclosed |
| US-5401699-A | Thermosensitive elements with color developers, fluoran derivatives and azaphthalides | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-4585483-A | Recording materials | FUJI PHOTO FILM CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| US-4179436-A | DYEING POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |