Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30669434 | 1.00 | PARP1 (0.43) | PARP1PARP2HRH3ABCB1KDM4E | |
| SCHEMBL30669428 | 0.99 | PARP1 (0.45) | PARP1PARP2HRH3ABCB1KDM4E | |
| SCHEMBL29164215 | 0.99 | PARP1 (0.45) | PARP1PARP2HRH3ABCB1KDM4E | |
| SCHEMBL29164218 | 0.90 | HRH3 (0.42) | PARP1PARP2HRH3KDM4EALDH1A1 | |
| SCHEMBL29164224 | 0.90 | PARP1 (0.48) | PARP1PARP2HRH3KDM4EALDH1A1 | |
| SCHEMBL30669438 | 0.90 | PARP1 (0.48) | PARP1PARP2HRH3KDM4EALDH1A1 | |
| SCHEMBL30669431 | 0.90 | HRH3 (0.42) | PARP1PARP2HRH3KDM4EALDH1A1 | |
| SCHEMBL29164230 | 0.79 | ALDH1A1 (0.44) | KDM4EALDH1A1GLAALOX15KMT2A | |
| SCHEMBL30669430 | 0.79 | ALDH1A1 (0.44) | KDM4EALDH1A1GLAALOX15KMT2A | |
| SCHEMBL4767000 | 0.75 | PARP1 (0.52) | PARP1PARP2HRH3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105916-B | Benzofuran compound and medical application thereof | 希格生科（深圳）有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117105916-A | Benzofuran compound and medical application thereof | 希格生科（深圳）有限公司 | 2023-11-24 | — | — | CN | disclosed |