Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Questiomycin B SCHEMBL3999786 | 0.79 | ALOX15 (1.00) | ALOX15TSHRALDH1A1HSD17B10MAPT | |
| Questiomycin B SCHEMBL24436 | 0.79 | — | — | |
| Questiomycin B SCHEMBL29430322 | 0.79 | — | — | |
| Questiomycin B SCHEMBL29077530 | 0.77 | ALOX15 (0.83) | ALOX15TSHRALDH1A1HSD17B10MAPT | |
| SCHEMBL18612812 | 0.77 | ALOX15 (0.94) | ALOX15TSHRALDH1A1HSD17B10MAPT | |
| Questiomycin B SCHEMBL3887270 | 0.77 | — | — | |
| Questiomycin B SCHEMBL11273511 | 0.77 | — | — | |
| Questiomycin B SCHEMBL31112025 | 0.77 | — | — | |
| Questiomycin B SCHEMBL11412866 | 0.77 | — | — | |
| Questiomycin B SCHEMBL4747619 | 0.77 | ALOX15 (0.94) | ALOX15TSHRALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112961891-B | Method for preparing icariin by using biphasic enzymatic reaction | 西安巨子生物基因技术股份有限公司 | 2024-01-26 | — | — | CN | disclosed |