Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.58 |
| ▸ | CDK2 | P24941 | 3/20 | 0.58 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.58 |
| ▸ | TYK2 | P29597 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132190 | 0.90 | CCNA2 (0.66) | RAB9ANPC1CCNA2CDK2CCNA1 | |
| SCHEMBL29164535 | 0.87 | TYK2 (0.53) | RAB9ANPC1CCNA2CDK2CCNA1 | |
| SCHEMBL29164825 | 0.85 | TYK2 (0.51) | RAB9ANPC1CCNA2CDK2CCNA1 | |
| SCHEMBL29164629 | 0.84 | CCNA2 (0.58) | RAB9ANPC1CCNA2CDK2CCNA1 | |
| SCHEMBL29164884 | 0.84 | TYK2 (0.50) | RAB9ANPC1CCNA2CDK2CCNA1 | |
| SCHEMBL29164892 | 0.83 | CCNA2 (0.67) | CCNA2CDK2CCNA1 | |
| SCHEMBL29164538 | 0.80 | TYK2 (0.57) | RAB9ATYK2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL29164793 | 0.79 | RAB9A (0.56) | RAB9ANPC1CCNA2CDK2CCNA1 | |
| SCHEMBL6339310 | 0.79 | NPC1 (0.66) | RAB9ANPC1CCNA2CDK2CCNA1 | |
| SCHEMBL6339700 | 0.77 | CCNA2 (0.82) | RAB9ANPC1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659001-A | Aminopyrimidine derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-03-08 | — | — | CN | disclosed |