Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43742 | 0.82 | KMT2A (0.61) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL27484392 | 0.81 | ALDH1A1 (0.48) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL666850 | 0.81 | ALDH1A1 (0.48) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL28575374 | 0.81 | CYP19A1 (0.47) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL28432678 | 0.81 | ELANE (0.45) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL22308226 | 0.80 | TET2 (0.45) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL27785600 | 0.80 | CYP19A1 (0.47) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL11815316 | 0.80 | ALDH1A1 (0.47) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| SCHEMBL11514392 | 0.80 | CYP19A1 (0.47) | PRSS1PRSS2PRSS3ALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL28310523 | 0.80 | ALDH1A1 (0.47) | PRSS1PRSS2PRSS3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447441-A | Difluoromethyl reagent and preparation method and application thereof | 深圳大学 | 2024-01-26 | — | — | CN | disclosed |