SCHEMBL29165397

SCHEMBL29165397

CCOC(=O)C(SC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.51
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
MMP8 P22894 1/20 0.48
PIN1 Q13526 1/20 0.44
MAPT P10636 2/20 0.43
MPO P05164 1/20 0.43
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CHRM4 P08173 1/20 0.42
CHRM1 P11229 1/20 0.42
CHRM3 P20309 1/20 0.42
GPR139 Q6DWJ6 1/20 0.41
TSHR P16473 1/20 0.41
PRNP P04156 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12892652 0.86 KDM4E (0.50) KDM4EKMT2AMEN1NPC1MMP8
SCHEMBL16841424 0.84 KMT2A (0.53) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL11780897 0.82 KDM4E (0.57) KDM4EKMT2AMEN1NPC1MMP8
SCHEMBL18113240 0.81 KMT2A (0.53) KDM4EKMT2AMEN1NPC1MMP8
SCHEMBL11780904 0.79 KDM4E (0.55) KDM4EKMT2AMEN1NPC1MMP8
SCHEMBL18113302 0.78 KMT2A (0.50) KMT2AMEN1NPC1MMP8PIN1
SCHEMBL18113060 0.78 KMT2A (0.50) KMT2AMEN1NPC1MMP8PIN1
SCHEMBL28870213 0.78 KDM4E (0.48) KDM4EKMT2AMEN1NPC1MMP8
SCHEMBL12975847 0.78 KDM4E (0.48) KDM4EKMT2AMEN1NPC1MMP8
SCHEMBL28870216 0.78 KDM4E (0.48) KDM4EKMT2AMEN1NPC1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119192444-A Water-soluble polymer, preparation method thereof and application thereof in grinding composition 武汉鼎泽新材料技术有限公司 2024-12-27 CN disclosed
CN-111615405-B Polymeric prodrugs and subcutaneous and/or intramuscular administration thereof 国家科学研究中心 2023-11-28 CN disclosed