Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11780897 | 0.86 | KDM4E (0.57) | KDM4EMMP8PIN1MEN1NPC1 | |
| SCHEMBL27864446 | 0.82 | KMT2A (0.58) | MEN1KMT2ASMN1; SMN2TSHRPKM | |
| SCHEMBL5277965 | 0.80 | ALDH1A1 (0.52) | KDM4EMMP8PIN1MEN1NPC1 | |
| SCHEMBL10415771 | 0.80 | KDM4E (0.49) | KDM4EMMP8PIN1MEN1NPC1 | |
| SCHEMBL29165397 | 0.79 | KDM4E (0.51) | KDM4EMMP8PIN1MEN1NPC1 | |
| SCHEMBL12892652 | 0.78 | KDM4E (0.50) | KDM4EMMP8PIN1MEN1NPC1 | |
| SCHEMBL10415772 | 0.78 | KDM4E (0.50) | KDM4EMMP8PIN1MEN1NPC1 | |
| SCHEMBL2027598 | 0.77 | MMP8 (0.56) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL29113676 | 0.76 | KDM4E (0.49) | KDM4EMMP8PIN1MEN1NPC1 | |
| SCHEMBL29113675 | 0.76 | POLB (0.50) | KDM4EMMP8PIN1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962214-A | Process for preparing amino substituted β-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3954731-A | Process for preparing 6-alkoxypenicillanic and 7-alkoxycephalosporin acids | ELI LILLY AND COMPANY (US) | 1976-05-04 | — | — | US | disclosed |