Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28679515 | 0.96 | LMNA (0.44) | LMNA | |
| Bromide SCHEMBL30839409 | 0.94 | LMNA (0.42) | LMNA | |
| SCHEMBL29165692 | 0.91 | LMNA (0.39) | LMNA | |
| Bromide SCHEMBL28661184 | 0.79 | LMNA (0.48) | LMNA | |
| SCHEMBL28692345 | 0.76 | LMNA (0.44) | LMNA | |
| SCHEMBL29165690 | 0.76 | LMNA (0.39) | LMNA | |
| SCHEMBL30721490 | 0.74 | LMNA (0.52) | LMNA | |
| SCHEMBL17664792 | 0.74 | LMNA (0.42) | LMNA | |
| SCHEMBL29165691 | 0.72 | LMNA (0.44) | LMNA | |
| SCHEMBL28661183 | 0.72 | LMNA (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717203-B | Preparation method of C5 Grignard reagent | 肇庆巨元生化有限公司 | 2024-01-19 | — | — | CN | disclosed |