SCHEMBL291657

SCHEMBL291657

[CH2]CSCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.48
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44
IDO1 P14902 3/20 0.43
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
MAOB P27338 1/20 0.42
POLB P06746 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CALM1 P0DP23 1/20 0.41
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
CTSL P07711 1/20 0.40
CTSB P07858 1/20 0.40
CA12 O43570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7554673 0.86 TSHR (0.37) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL206 0.83 CYP2C19 (0.56) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5209418 0.80 CYP2C19 (0.54) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5209412 0.80 CYP2C19 (0.54) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL7136112 0.80 CYP2C19 (0.54) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL934486 0.80 CYP2C19 (0.55) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL11465830 0.78 CYP2C19 (0.56) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8541503 0.78 CYP2C19 (0.52) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL3078147 0.78 CYP2C19 (0.64) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL7138153 0.78 CYP2C19 (0.56) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114247566-A High-sulfur bauxite desulfurization and desilication flotation collecting agent and integrated flotation method 中南大学 2022-03-29 CN claimed
CN-107075121-B Polysiloxane copolymers or terpolymers and polymers made therefrom 莫门蒂夫性能材料股份有限公司 2021-01-22 CN claimed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
CN-108722677-B A kind of O- alkyl-S- hydroxyalkyl xanthate collecting agent and its preparation and application 中南大学 2019-06-07 CN claimed
CN-108722677-A A kind of O- alkyl-S- hydroxyalkyl xanthate collecting agents and its preparation and application 中南大学 2018-11-02 CN claimed
EP-3323414-A1 INHIBITORS OF NEDD8-ACTIVATING ENZYME Millennium Pharmaceuticals, Inc. (US) 2018-05-23 EP claimed
EP-2727915-B1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof CONCERT PHARMACEUTICALS INC (US) 2016-04-13 EP claimed
CN-102617684-B Compound and preparation method thereof CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY SHIJIAZHUANG CO LTD 2014-07-16 CN claimed
EP-2727915-A1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof Concert Pharmaceuticals Inc. (US) 2014-05-07 EP claimed
CN-102617684-A Compound and preparation method thereof CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY SHIJIAZHUANG CO LTD 2012-08-01 CN claimed
EP-0076557-B1 PEPTIDES AND PSEUDOPEPTIDES IN WHICH THE N TERMINUS BEARS TWO SUBSTITUENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-13 EP claimed
US-4544652-A α-Hydroxyethylphosphinates, and their use as fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-10-01 US claimed
US-4421744-A OPIATE RECEPTOR ANTAGONISTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-20 US claimed
EP-0093010-A2 Alpha-hydroxyethylphosphinates, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-02 EP claimed
EP-0076557-A2 Peptides and pseudopeptides in which the N terminus bears two substituents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-13 EP claimed
US-4182891-A ENZYME INHIBITORS, IMMUNOSUPPRESSANTS, CONTROL OF NEOPLASTIC GROWTH MERRELL TORAUDE ET COMPAGNIE (FR) 1980-01-08 US claimed
US-4139563-A ENZYME INHIBITORS, ANTIFERTILITY AGENTS, IMMUNOSUPPRESSIVES, ANTITUMOR AGENTS MERRELL TORAUDE ET COMPAGNIE (FR) 1979-02-13 US claimed
US-4134918-A ENZYME INHIBITORS, ANTIBODY INHIBITORS MERRELL TORAUDE ET COMPAGNIE (FR) 1979-01-16 US claimed
US-3953437-A Process of preparing cephalosporanic acid ester derivatives YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-04-27 US claimed
US-3935198-A BY HEATING THE PENICILLIN SULFOXIDE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-01-27 US claimed