Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30476805 | 1.00 | HDAC7 (0.52) | HDAC7HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL14417309 | 0.85 | NPC1 (0.49) | HDAC7HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL29166106 | 0.83 | HDAC7 (0.53) | HDAC7HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL10928482 | 0.83 | HDAC7 (0.56) | HDAC7HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL2483573 | 0.82 | HDAC1 (0.52) | HDAC7HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL7370340 | 0.81 | HSD17B10 (0.51) | HDAC7HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL23782525 | 0.81 | HDAC1 (0.51) | HDAC7HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL23782546 | 0.80 | HDAC7 (0.50) | HDAC7HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL30476796 | 0.78 | HDAC1 (0.48) | HDAC7HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL7810615 | 0.76 | GAA (0.52) | KMT2AMEN1HSD17B10HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460743-A | Small molecule VE-PTP inhibitors | 曼宁研究公司 | 2024-01-26 | — | — | CN | disclosed |