Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30278697 | 0.86 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HPGDHTTKDM4E | |
| SCHEMBL11773628 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HSD17B10HPGDHTTKDM4E | |
| SCHEMBL29256396 | 0.85 | ASAH1 (0.49) | ALDH1A1HSD17B10HPGDHTTKDM4E | |
| SCHEMBL8446739 | 0.84 | TP53 (0.51) | ALDH1A1HSD17B10HPGDHTTKDM4E | |
| SCHEMBL24130616 | 0.83 | ALDH1A1 (0.64) | HDAC1HDAC7ALDH1A1HDAC8HDAC3 | |
| SCHEMBL7370340 | 0.83 | HSD17B10 (0.51) | HDAC1HDAC7ALDH1A1HDAC8HDAC3 | |
| SCHEMBL21851961 | 0.83 | ALDH1A1 (0.64) | HDAC1HDAC7ALDH1A1HDAC8HDAC3 | |
| SCHEMBL30299434 | 0.83 | ALDH1A1 (0.64) | HDAC1HDAC7ALDH1A1HDAC8HDAC3 | |
| Hydrochloric Acid SCHEMBL4804796 | 0.83 | TP53 (0.50) | ALDH1A1HSD17B10HPGDHTTKDM4E | |
| SCHEMBL29166106 | 0.83 | HDAC7 (0.53) | HDAC1HDAC7ALDH1A1HDAC8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017358-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2004-08-11 | — | — | EP | claimed |
| EP-1017358-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 2000-07-12 | — | — | EP | claimed |
| US-5939458-A | APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN | GILLETTE COMPANY, THE | 1999-08-17 | — | — | US | claimed |
| WO-1999015136-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 1999-04-01 | — | — | WO | claimed |
| EP-3212183-B1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIV ROCHESTER (US) | 2019-10-02 | — | — | EP | disclosed |
| US-10028931-B2 | Synergistic compositions for treating microbial infections | UNIVERSITY OF ROCHESTER (US) | 2018-07-24 | — | — | US | disclosed |
| EP-3212183-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | University of Rochester (US) | 2017-09-06 | — | — | EP | disclosed |
| US-20170246139-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIVERSITY OF ROCHESTER (US) | 2017-08-31 | — | — | US | disclosed |
| WO-2016070021-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | UNIVERSITY OF ROCHESTER (US) | 2016-05-06 | — | — | WO | disclosed |
| CN-102348807-B | Mono charging system for selectively introducing non-native amino acids into proteins using an in vitro protein synthesis system | SUTRO BIOPHARMA INC | 2015-04-15 | — | — | CN | disclosed |
| US-8778631-B2 | Mono charging system for selectively introducing non-native amino acids into proteins using an in vitro protein synthesis system | SUTRO BIOPHARMA, INC. (US) | 2014-07-15 | — | — | US | disclosed |
| EP-2376647-B1 | MONO CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO PROTEIN SYNTHESIS SYSTEM | SUTRO BIOPHARMA INC (US) | 2014-03-05 | — | — | EP | disclosed |
| US-20100184134-A1 | DUAL CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO SYNTHESIS METHOD | SUTRO BIOPHARMA, INC. (US) | 2010-07-22 | — | — | US | disclosed |
| US-20100184135-A1 | MONO CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO PROTEIN SYNTHESIS SYSTEM | SUTRO BIOPHARMA, INC. (US) | 2010-07-22 | — | — | US | disclosed |
| WO-2010081110-A1 | DUAL CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO SYNTHESIS METHOD | SUTRO BIOPHARMA, INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| WO-2010081111-A1 | MONO CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO PROTEIN SYNTHESIS SYSTEM | SUTRO BIOPHARMA, INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| EP-1017358-B1 | REDUCTION OF HAIR GROWTH | GILLETTE CO (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1017358-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 2000-07-12 | — | — | EP | disclosed |
| US-5939458-A | APPLYING AN INHIBITOR OF AMINOACYL-TRNA SYNTHETASE TO THE SKIN | GILLETTE COMPANY, THE | 1999-08-17 | — | — | US | disclosed |
| WO-1999015136-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 1999-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10028931-B2 | Synergistic compositions for treating microbial infections | RNASE1, RNASEL, RNASEH1 | HDAC1 1400/4885HDAC7 771/4885ALDH1A1 3822/4885 |
| US-20170246139-A1 | SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS | RNASE1, RNASEL, RNASEH1 | HDAC1 1400/4885HDAC7 771/4885ALDH1A1 3822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.