Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | HPGD | P15428 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | PPARG | P37231 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL925411 | 0.87 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| 3,6-Dimethoxyflavone SCHEMBL4649913 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL9387213 | 0.85 | KDM4E (0.74) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL29167450 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL972002 | 0.84 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10CYP3A4MAPT | |
| SCHEMBL27325970 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL926613 | 0.83 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL928086 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL28565701 | 0.82 | ABCG2 (0.69) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL1030897 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645594-A | Preparation method of oroxylin A | 南京杰运医药科技有限公司 | 2024-03-05 | — | — | CN | disclosed |