Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.35 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22996519 | 1.00 | MAP4K1 (0.38) | MAP4K1CD274PDCD1LG2PIK3CAALK | |
| SCHEMBL18361541 | 1.00 | MAP4K1 (0.38) | MAP4K1CD274PDCD1LG2PIK3CAALK | |
| Hydrochloric Acid SCHEMBL23500987 | 0.98 | MAP4K1 (0.38) | MAP4K1CD274PDCD1LG2PIK3CAALK | |
| Hydrochloric Acid SCHEMBL23500986 | 0.98 | MAP4K1 (0.38) | MAP4K1CD274PDCD1LG2PIK3CAALK | |
| Hydrochloric Acid SCHEMBL30512171 | 0.98 | MAP4K1 (0.38) | MAP4K1CD274PDCD1LG2PIK3CAALK | |
| SCHEMBL25171167 | 0.88 | MAP4K1 (0.34) | MAP4K1CD274PDCD1LG2PIK3CAALK | |
| SCHEMBL30395524 | 0.88 | MAP4K1 (0.34) | MAP4K1CD274PDCD1LG2PIK3CAALK | |
| SCHEMBL25171166 | 0.88 | MAP4K1 (0.34) | MAP4K1CD274PDCD1LG2PIK3CAALK | |
| SCHEMBL15150582 | 0.87 | P2RX3 (0.35) | MAP4K1PIK3CAMAPTCASP1P2RX3 | |
| SCHEMBL25224803 | 0.84 | SCN9A (0.33) | MAP4K1PIK3CAMAPTCASP1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624166-A | Triazole derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117586277-A | Macrocyclic triazole derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-02-23 | — | — | CN | disclosed |