Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168188 | 1.00 | LMNA (0.38) | LMNATSHRPPARGNCOA2NCOA1 | |
| SCHEMBL30133680 | 1.00 | LMNA (0.38) | LMNATSHRPPARGNCOA2NCOA1 | |
| SCHEMBL29168215 | 0.87 | KMT2A (0.40) | LMNATSHRTRPA1CA1CA2 | |
| SCHEMBL29168044 | 0.87 | KMT2A (0.40) | LMNATSHRTRPA1CA1CA2 | |
| SCHEMBL29168047 | 0.87 | KMT2A (0.40) | LMNATSHRTRPA1CA1CA2 | |
| SCHEMBL29168067 | 0.81 | MAPK1 (0.39) | LMNATSHRMAPK1HSD17B10MAPT | |
| SCHEMBL30133692 | 0.81 | MAPK1 (0.39) | LMNATSHRMAPK1HSD17B10MAPT | |
| SCHEMBL29168065 | 0.81 | MAPK1 (0.39) | LMNATSHRMAPK1HSD17B10MAPT | |
| SCHEMBL29168292 | 0.81 | CASR (0.33) | LMNAMAPTHPGDALDH1A1KMT2A | |
| SCHEMBL30133663 | 0.80 | AAK1 (0.37) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |