Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29169640 | 1.00 | FAAH (0.55) | FAAHHSP90AA1DNM1TSHRMEN1 | |
| SCHEMBL10397476 | 0.91 | FAAH (0.57) | FAAHHSP90AA1DNM1TSHRMEN1 | |
| Bromide SCHEMBL28563242 | 0.84 | HSP90AA1 (0.52) | FAAHHSP90AA1DNM1TSHRMEN1 | |
| SCHEMBL17105834 | 0.84 | HSP90AA1 (0.55) | FAAHHSP90AA1DNM1TSHRMEN1 | |
| SCHEMBL29174060 | 0.84 | HSP90AA1 (0.55) | FAAHHSP90AA1DNM1TSHRMEN1 | |
| SCHEMBL29174034 | 0.84 | HSP90AA1 (0.55) | FAAHHSP90AA1DNM1TSHRMEN1 | |
| SCHEMBL28987996 | 0.84 | HSP90AA1 (0.55) | FAAHHSP90AA1DNM1TSHRMEN1 | |
| SCHEMBL25394342 | 0.82 | HSP90AA1 (0.53) | FAAHHSP90AA1DNM1TSHRMEN1 | |
| SCHEMBL23040950 | 0.82 | HSP90AA1 (0.53) | FAAHHSP90AA1DNM1TSHRMEN1 | |
| SCHEMBL25395101 | 0.82 | HSP90AA1 (0.53) | FAAHHSP90AA1DNM1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143584-A | Slick water system based on amphiphilic polymer and preparation method thereof | 四川川庆井下科技有限公司 | 2023-12-01 | — | — | CN | claimed |
| CN-117143584-A | Slick water system based on amphiphilic polymer and preparation method thereof | 四川川庆井下科技有限公司 | 2023-12-01 | — | — | CN | disclosed |