Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 12/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29170125 | 1.00 | HCAR3 (0.53) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30087167 | 0.91 | MAPT (0.46) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30087168 | 0.91 | MAPT (0.46) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL29170112 | 0.91 | MAPT (0.46) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL29170113 | 0.91 | MAPT (0.46) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL30966512 | 0.89 | HCAR3 (0.51) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL27205213 | 0.85 | HCAR3 (0.47) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL27176916 | 0.85 | HCAR3 (0.47) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL23273541 | 0.83 | HCAR3 (0.55) | HCAR3MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL23273542 | 0.83 | HCAR3 (0.55) | HCAR3MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344349-A | 4-Alkoxybenzimidazole-6-carboxylic acid derivatives as GLP-1 receptor agonists | 中国科学院上海药物研究所 | 2024-07-16 | — | — | CN | disclosed |
| CN-118103366-A | Certain 2, 5-diazabicyclo [4.2.0] octanes as GLP-1 receptor modulators | 阿斯利康(瑞典)有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117355517-A | Macrocyclic glucagon-like peptide 1 receptor agonists | 伊莱利利公司 | 2024-01-05 | — | — | CN | disclosed |