Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23603812 | 1.00 | BTK (0.41) | BTKKDM1AMAOBEPHX1CTSK | |
| SCHEMBL25070777 | 1.00 | BTK (0.41) | BTKKDM1AMAOBEPHX1CTSK | |
| SCHEMBL15373088 | 0.88 | BTK (0.42) | BTKKDM1AMAOBEPHX1CTSK | |
| SCHEMBL15297550 | 0.88 | BTK (0.42) | BTKKDM1AMAOBEPHX1CTSK | |
| SCHEMBL15373059 | 0.88 | BTK (0.42) | BTKKDM1AMAOBEPHX1CTSK | |
| SCHEMBL30199537 | 0.82 | DRD2 (0.41) | BTKKDM1AMAOBEPHX1CTSK | |
| SCHEMBL2971990 | 0.82 | BTK (0.46) | BTKKDM1AMAOBEPHX1CTSK | |
| SCHEMBL2971993 | 0.82 | BTK (0.46) | BTKKDM1AMAOBEPHX1CTSK | |
| SCHEMBL15009122 | 0.82 | BTK (0.49) | BTKKDM1AMAOBEPHX1CTSK | |
| SCHEMBL16308056 | 0.82 | HCAR2 (0.40) | ALDH1A1CA1CA2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715903-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 新基公司 | 2024-03-15 | — | — | CN | disclosed |