Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30198901 | 1.00 | NR1H2 (0.43) | NR1H2ALDH1A1HPGDKDM4EGLA | |
| SCHEMBL29170267 | 1.00 | NR1H2 (0.43) | NR1H2ALDH1A1HPGDKDM4EGLA | |
| SCHEMBL30472901 | 0.93 | NR1H2 (0.40) | NR1H2ALDH1A1HPGDKDM4EGLA | |
| SCHEMBL13744392 | 0.86 | NR1H2 (0.44) | NR1H2ALDH1A1HPGDKDM4EGLA | |
| SCHEMBL30199567 | 0.86 | NR1H2 (0.44) | NR1H2ALDH1A1HPGDTSHRMEN1 | |
| SCHEMBL13567960 | 0.83 | ALDH1A1 (0.40) | NR1H2ALDH1A1HPGDKDM4EGLA | |
| SCHEMBL13568018 | 0.83 | ALDH1A1 (0.40) | NR1H2ALDH1A1HPGDKDM4EGLA | |
| SCHEMBL3314363 | 0.83 | NR1H2 (0.47) | NR1H2ALDH1A1HPGDRECQLMEN1 | |
| SCHEMBL3314366 | 0.83 | NR1H2 (0.47) | NR1H2ALDH1A1HPGDRECQLMEN1 | |
| SCHEMBL10264379 | 0.83 | NR1H2 (0.49) | NR1H2ALDH1A1HPGDRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715903-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 新基公司 | 2024-03-15 | — | — | CN | disclosed |