Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.46 |
| ▸ | FNTB | P49356 | 8/20 | 0.46 |
| ▸ | HRAS | P01112 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 1/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171480 | 1.00 | FNTA (0.46) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL21877258 | 0.89 | FNTA (0.61) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL18041272 | 0.89 | FNTA (0.61) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL18041271 | 0.89 | FNTA (0.61) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL29171478 | 0.71 | FNTA (0.79) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL21905458 | 0.70 | HRH3 (0.43) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL10149143 | 0.68 | CYP2C9 (0.70) | CYP2C9 | |
| SCHEMBL10039032 | 0.65 | FNTA (0.80) | FNTAFNTBHRASKRASPGGT1B | |
| SCHEMBL17547679 | 0.65 | FNTA (0.80) | FNTAFNTBHRASKRASPGGT1B | |
| Bms-214662 SCHEMBL94663 | 0.63 | FNTA (1.00) | FNTAFNTBHRASKRASPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693341-A | Repentinib for the treatment of melanoma | 德西费拉制药有限责任公司 | 2024-03-12 | — | — | CN | disclosed |