Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | BLM | P54132 | 2/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | QDPR | P09417 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140947 | 0.86 | TSHR (1.00) | TSHRBLMNPSR1CYP3A4NFKB1 | |
| SCHEMBL10085823 | 0.86 | TSHR (1.00) | TSHRBLMNPSR1CYP3A4NFKB1 | |
| SCHEMBL1243722 | 0.86 | TSHR (1.00) | TSHRBLMNPSR1CYP3A4NFKB1 | |
| SCHEMBL134326 | 0.86 | TSHR (1.00) | TSHRBLMNPSR1CYP3A4NFKB1 | |
| SCHEMBL18255548 | 0.86 | ACHE (0.57) | TSHRBLMNPSR1CYP3A4KMT2A | |
| SCHEMBL10784788 | 0.85 | TSHR (0.97) | TSHRBLMNPSR1CYP3A4NFKB1 | |
| SCHEMBL28717780 | 0.85 | TSHR (0.97) | TSHRBLMNPSR1CYP3A4NFKB1 | |
| SCHEMBL29538919 | 0.85 | TSHR (0.73) | TSHRBLMNPSR1CYP3A4NFKB1 | |
| SCHEMBL13816533 | 0.85 | TSHR (0.73) | TSHRBLMNPSR1CYP3A4NFKB1 | |
| SCHEMBL6216595 | 0.85 | BLM (0.73) | TSHRBLMNPSR1CYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683820-A | Method for preparing aromatic alpha-hydroxy ketone by utilizing acetohydroxy acid synthase | 厦门大学 | 2024-03-12 | — | — | CN | claimed |
| CN-117683820-A | Method for preparing aromatic alpha-hydroxy ketone by utilizing acetohydroxy acid synthase | 厦门大学 | 2024-03-12 | — | — | CN | disclosed |