Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 9/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 11/20 | 0.58 |
| ▸ | INSR | P06213 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32685271 | 1.00 | MAP4K1 (0.59) | MAP4K1ALKINSR | |
| Hydrochloric Acid SCHEMBL30446771 | 0.99 | MAP4K1 (0.59) | MAP4K1ALKINSR | |
| Hydrochloric Acid SCHEMBL25339312 | 0.99 | MAP4K1 (0.59) | MAP4K1ALKINSR | |
| SCHEMBL29172265 | 0.93 | ALK (0.63) | MAP4K1ALKINSR | |
| SCHEMBL25947735 | 0.91 | MAP4K1 (0.62) | MAP4K1ALKINSR | |
| SCHEMBL25947485 | 0.91 | ALK (0.61) | ALKINSR | |
| Hydrochloric Acid SCHEMBL25436527 | 0.90 | MAP4K1 (0.59) | MAP4K1ALKINSR | |
| SCHEMBL31315699 | 0.89 | MAP4K1 (0.75) | MAP4K1ALKINSR | |
| SCHEMBL25947722 | 0.89 | MAP4K1 (0.75) | MAP4K1ALKINSR | |
| SCHEMBL29172268 | 0.89 | MAP4K1 (0.60) | MAP4K1ALKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730083-A | Pyrimidine compounds as MAP4K1 inhibitors | 格兰马克专业公司 | 2024-03-19 | — | — | CN | claimed |