Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 9/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 11/20 | 0.58 |
| ▸ | INSR | P06213 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172271 | 1.00 | MAP4K1 (0.59) | MAP4K1ALKINSR | |
| Hydrochloric Acid SCHEMBL30446771 | 0.99 | MAP4K1 (0.59) | MAP4K1ALKINSR | |
| Hydrochloric Acid SCHEMBL25339312 | 0.99 | MAP4K1 (0.59) | MAP4K1ALKINSR | |
| SCHEMBL29172265 | 0.93 | ALK (0.63) | MAP4K1ALKINSR | |
| SCHEMBL25947735 | 0.91 | MAP4K1 (0.62) | MAP4K1ALKINSR | |
| SCHEMBL25947485 | 0.91 | ALK (0.61) | ALKINSR | |
| Hydrochloric Acid SCHEMBL25436527 | 0.90 | MAP4K1 (0.59) | MAP4K1ALKINSR | |
| SCHEMBL31315699 | 0.89 | MAP4K1 (0.75) | MAP4K1ALKINSR | |
| SCHEMBL25947722 | 0.89 | MAP4K1 (0.75) | MAP4K1ALKINSR | |
| SCHEMBL29172268 | 0.89 | MAP4K1 (0.60) | MAP4K1ALKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12577267-B2 | Pyrimidine compounds for use as MAP4K1 inhibitors | GLENMARK SPECIALITY S.A. (CH) | 2026-03-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577267-B2 | Pyrimidine compounds for use as MAP4K1 inhibitors | PTK2B, MAP3K10, MAP3K20 | MAP4K1 23/4885ALK 150/4885INSR 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.