Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172297 | 0.86 | NPC1 (0.49) | MAOBMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL25339187 | 0.80 | MAOB (0.50) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL23273762 | 0.78 | MAOB (0.50) | PDGFRBPDGFRAMAOBGAAMAPT | |
| SCHEMBL1330323 | 0.75 | MAOB (0.50) | PDGFRBPDGFRAMAOBGAAMAPT | |
| SCHEMBL29172318 | 0.74 | MAOB (0.57) | MAOBMAOAMEN1KMT2AALOX5 | |
| SCHEMBL30183962 | 0.74 | MAOB (0.57) | MAOBMAOAMEN1KMT2AALOX5 | |
| Phosphine SCHEMBL24869922 | 0.72 | LTA4H (0.50) | PDGFRBPDGFRAMAOBGAAMAPT | |
| SCHEMBL7409633 | 0.72 | MAOB (0.50) | PDGFRBPDGFRAMAOBGAAMAPT | |
| SCHEMBL504815 | 0.70 | MAOB (0.60) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL29870411 | 0.70 | NPC1 (0.55) | PDGFRBPDGFRAMAOBRAB9ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730083-A | Pyrimidine compounds as MAP4K1 inhibitors | 格兰马克专业公司 | 2024-03-19 | — | — | CN | disclosed |