Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16976217 | 1.00 | LMNA (0.57) | LMNACYP2D6SMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL21302016 | 1.00 | LMNA (0.57) | LMNACYP2D6SMN1; SMN2HIF1ACYP3A4 | |
| Hydrochloric Acid SCHEMBL1311458 | 0.98 | LMNA (0.55) | LMNACYP2D6SMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL8228203 | 0.87 | LMNA (0.55) | LMNACYP2D6SMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL14898399 | 0.87 | LMNA (0.55) | LMNACYP2D6SMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL7368328 | 0.85 | LMNA (0.53) | LMNACYP2D6SMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL25583339 | 0.85 | BLM (0.59) | LMNACYP2D6SMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL11495672 | 0.85 | SMN1; SMN2 (0.50) | LMNACYP2D6SMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL11495669 | 0.85 | SMN1; SMN2 (0.50) | LMNACYP2D6SMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL31195757 | 0.84 | HPGD (0.45) | LMNACYP2D6SMN1; SMN2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117202938-A | Variant Fc domains and uses thereof | 奇达拉治疗公司 | 2023-12-08 | — | — | CN | disclosed |