Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21365261 | 0.88 | CYP3A4 (0.42) | CYP3A4LMNAPSMB5BCL2A1TSHR | |
| SCHEMBL30301237 | 0.83 | CYP3A4 (0.70) | CYP3A4LMNATP53TSHRALDH1A1 | |
| SCHEMBL17666071 | 0.83 | PSMB5 (0.51) | PSMB5BCL2A1ALDH1A1TDP1RAB9A | |
| SCHEMBL17652265 | 0.81 | GSTO1 (0.51) | LMNAPSMB5BCL2A1TP53ALDH1A1 | |
| SCHEMBL17078095 | 0.80 | TSHR (0.48) | CYP3A4LMNATP53TSHRALDH1A1 | |
| SCHEMBL6692681 | 0.80 | TSHR (0.44) | CYP3A4LMNATP53TSHRALDH1A1 | |
| SCHEMBL29173202 | 0.78 | BCL2A1 (0.49) | CYP3A4LMNABCL2A1TSHRALDH1A1 | |
| SCHEMBL4294748 | 0.78 | TSHR (0.43) | CYP3A4LMNATP53TSHRALDH1A1 | |
| SCHEMBL21494199 | 0.78 | CYP3A4 (0.43) | CYP3A4LMNATP53TSHRALDH1A1 | |
| SCHEMBL5685210 | 0.78 | PSMB5 (0.40) | PSMB5BCL2A1ALDH1A1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384081-A | Indolone derivative and preparation method and application thereof | 上海筛杰生物医药有限公司 | 2024-01-12 | — | — | CN | disclosed |