Quinoline

Quinoline

SCHEMBL29173271

c1ccc2c(c1)ccc1ccncc12.c1ccc2ncccc2c1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.59
ALDH1A1 P00352 4/20 0.59
MAPK10 P53779 2/20 0.49
KDM4E B2RXH2 3/20 0.45
HTT P42858 2/20 0.45
TNF P01375 1/20 0.45
POLB P06746 1/20 0.45
RAD52 P43351 1/20 0.45
LMNA P02545 2/20 0.44
GPR3 P46089 1/20 0.44
CYP2A6 P11509 2/20 0.42
NCOA3 Q9Y6Q9 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PDGFRB P09619 1/20 0.41
PDGFRA P16234 1/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
CASP1 P29466 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenanthrene SCHEMBL28062390 0.87 ALDH1A1 (0.77) CYP3A4ALDH1A1KDM4EHTTPOLB
Phenanthrene SCHEMBL28090206 0.85 ALDH1A1 (0.74) CYP3A4ALDH1A1KDM4EHTTPOLB
SCHEMBL15077 0.85 ALDH1A1 (0.57) CYP3A4ALDH1A1MAPK10KDM4EHTT
SCHEMBL29568863 0.84 CYP3A4 (0.66) CYP3A4MAPK10KDM4EHTTTNF
SCHEMBL1419153 0.84 CYP3A4 (0.66) CYP3A4MAPK10KDM4EHTTTNF
SCHEMBL29035751 0.83 KDM4E (0.55) CYP3A4ALDH1A1MAPK10KDM4EHTT
Isoquinoline SCHEMBL27938240 0.82 ALDH1A1 (0.68) CYP3A4ALDH1A1KDM4EHTTPOLB
Isoquinoline SCHEMBL1505711 0.82 ALDH1A1 (0.68) CYP3A4ALDH1A1KDM4EHTTPOLB
Quinoline SCHEMBL28269861 0.82 CYP3A4 (0.88) CYP3A4ALDH1A1KDM4EHTTPOLB
SCHEMBL30858829 0.81 HPRT1 (0.61) CYP3A4ALDH1A1MAPK10KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736223-A Organic compound, electro-optical device including the same, and electronic apparatus 三星显示有限公司 2024-03-22 CN disclosed