SCHEMBL2917397

SCHEMBL2917397

CCCCCC(CC)COC(=O)C1(C(=O)OCC(CC)CCCCC)CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.49
TSHR P16473 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
ATM Q13315 1/20 0.49
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
ALDH1A1 P00352 7/20 0.43
CA2 P00918 3/20 0.43
MAPK1 P28482 3/20 0.42
RECQL P46063 1/20 0.42
LMNA P02545 3/20 0.40
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
ZDHHC7 Q9NXF8 1/20 0.37
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35
MMP14 P50281 1/20 0.35
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2919402 0.95 CYP3A4 (0.54) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL2917410 0.91 PRSS1 (0.39) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL3768684 0.89 CYP3A4 (0.41) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL11895929 0.82 ACE2 (0.41) PRSS1PRSS2PRSS3ALDH1A1ZDHHC7
SCHEMBL19595702 0.82 CYP3A4 (0.53) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL28870685 0.81 CYP3A4 (0.54) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL2917189 0.80 CYP3A4 (0.50) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL11216636 0.79 CYP3A4 (0.55) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL15934 0.78 CYP3A4 (0.51) CYP3A4TSHRTDP1ATMPRSS1
SCHEMBL15658731 0.78 CYP3A4 (0.51) CYP3A4TSHRTDP1ATMPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2220154-B1 C7-C12 SECONDARY ALCOHOL ESTERS OF CYCLOHEXANOIC ACID EXXONMOBIL CHEM PATENTS INC (US) 2014-06-18 EP disclosed
US-8669311-B2 C7—C12 secondary alcohol esters of cyclohexanoic acid EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-03-11 US disclosed
US-20100305250-A1 C7-C12 Secondary Alcohol Esters of Cyclohexanoic Acid EXXONMOBIL CHEMICAL PATENTS INC. 2010-12-02 US disclosed
EP-2220154-A1 C7-C12 SECONDARY ALCOHOL ESTERS OF CYCLOHEXANOIC ACID ExxonMobil Chemical Patents Inc. (US) 2010-08-25 EP disclosed
WO-2009070398-A1 C7-C12 SECONDARY ALCOHOL ESTERS OF CYCLOHEXANOIC ACID EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-06-04 WO disclosed