SCHEMBL3768684

SCHEMBL3768684

CCCC(CC)COC(=O)C1(C(=O)OCC(CC)CCC)CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.41
TSHR P16473 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
ATM Q13315 1/20 0.41
ALDH1A1 P00352 4/20 0.37
CA2 P00918 1/20 0.37
MAPK1 P28482 2/20 0.36
RECQL P46063 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
LMNA P02545 3/20 0.34
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2919402 0.91 CYP3A4 (0.54) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL2917397 0.89 CYP3A4 (0.49) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL2917410 0.86 PRSS1 (0.39) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL19595702 0.77 CYP3A4 (0.53) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL16949830 0.75 TSHR (0.39) CYP3A4TSHRTDP1ALDH1A1LMNA
SCHEMBL232259 0.75 TSHR (0.39) CYP3A4TSHRTDP1ALDH1A1LMNA
SCHEMBL28870685 0.75 CYP3A4 (0.54) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL2917189 0.75 CYP3A4 (0.50) CYP3A4TSHRTDP1ATMALDH1A1
SCHEMBL11895929 0.74 ACE2 (0.41) ALDH1A1PRSS1PRSS2PRSS3
SCHEMBL234284 0.73 CYP3A4 (0.41) CYP3A4TSHRTDP1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100310891-A1 Compositions Based on C4-C7 Secondary Aliphatic Alcohol Esters of Cyclohexanecarboxylic Acids EXXONMOBIL CHEMICAL PATENTS INC. 2010-12-09 US disclosed
WO-2009070399-A1 COMPOSITIONS BASED ON C4-C7 SECONDARY ALIPHATIC ALCOHOL ESTERS OF CYCLOHEXANECARBOXYLIC ACIDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-06-04 WO disclosed