Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAP3K12 | Q12852 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21355413 | 0.91 | TNKS (0.52) | TNKSTNKS2HTTKMT2AMAP3K12 | |
| SCHEMBL29174308 | 0.88 | HTT (0.49) | TNKSTNKS2HTTKMT2AMAP3K12 | |
| SCHEMBL30868243 | 0.84 | TNKS (0.47) | TNKSTNKS2HTTMAP3K12MAPK1 | |
| SCHEMBL30217691 | 0.84 | HTT (0.54) | HTTKMT2ACYP11B1CYP11B2JAK2 | |
| SCHEMBL322329 | 0.84 | HTT (0.54) | HTTKMT2ACYP11B1CYP11B2JAK2 | |
| SCHEMBL16456396 | 0.84 | TNKS (0.50) | TNKSTNKS2HTTMAP3K12MAPK1 | |
| SCHEMBL16442375 | 0.81 | TNKS (0.45) | TNKSTNKS2HTT | |
| SCHEMBL16456383 | 0.80 | TNKS (0.47) | TNKSTNKS2MAP3K12MAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL17866318 | 0.79 | TNKS (0.44) | TNKSTNKS2HTT | |
| SCHEMBL2250114 | 0.72 | HTT (0.52) | TNKSTNKS2HTTKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396474-A | Plasma kallikrein inhibitors | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |