Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | MAP3K12 | Q12852 | 4/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21355413 | 0.93 | TNKS (0.52) | TNKSTNKS2MAP3K12CSNK1A1CLK4 | |
| SCHEMBL16456396 | 0.86 | TNKS (0.50) | TNKSTNKS2MAP3K12CSNK1A1CLK4 | |
| SCHEMBL16442375 | 0.86 | TNKS (0.45) | TNKSTNKS2HTTCHEK1CCNA2 | |
| SCHEMBL29174308 | 0.84 | HTT (0.49) | TNKSTNKS2MAP3K12CSNK1A1CLK4 | |
| SCHEMBL29174253 | 0.84 | TNKS (0.47) | TNKSTNKS2MAP3K12CSNK1A1CLK4 | |
| Hydrochloric Acid SCHEMBL17866318 | 0.84 | TNKS (0.44) | TNKSTNKS2HTTCHEK1CCNA2 | |
| SCHEMBL16456383 | 0.82 | TNKS (0.47) | TNKSTNKS2MAP3K12PKMMAPK1 | |
| SCHEMBL19937861 | 0.74 | TNKS (0.40) | TNKSTNKS2MAP3K12PKM | |
| SCHEMBL7898980 | 0.74 | HTT (0.44) | TNKSTNKS2CSNK1A1CLK4HTT | |
| SCHEMBL30867934 | 0.74 | PDGFRB (0.41) | PDGFRBPDGFRAPSMB5HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025131978-A1 | DRUG-LINKER REAGENTS FOR CONJUGATION | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2025-06-26 | — | — | WO | disclosed |
| WO-2024028169-A1 | NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2024-02-08 | — | — | WO | disclosed |