Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.47 |
| ▸ | CDK9 | P50750 | 5/20 | 0.47 |
| ▸ | CDK7 | P50613 | 3/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174688 | 0.87 | HDAC3 (0.47) | HDAC3HDAC1CDK9CDK7RPS6KB1 | |
| SCHEMBL30725499 | 0.87 | HDAC3 (0.47) | HDAC3HDAC1CDK9CDK7RPS6KB1 | |
| SCHEMBL29174650 | 0.84 | HDAC3 (0.50) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174666 | 0.83 | MEN1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174654 | 0.82 | MEN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174676 | 0.82 | JAK3 (0.59) | HDAC3HDAC1CDK9CDK7RPS6KB1 | |
| SCHEMBL29174721 | 0.81 | MEN1 (0.46) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174722 | 0.80 | MEN1 (0.51) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174600 | 0.79 | MEN1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL30725441 | 0.78 | MEN1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |