Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174610 | 0.85 | MEN1 (0.52) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174664 | 0.83 | MAPT (0.50) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174666 | 0.82 | MEN1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174650 | 0.80 | HDAC3 (0.50) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174600 | 0.79 | MEN1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174698 | 0.78 | MEN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174722 | 0.77 | MEN1 (0.51) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29174625 | 0.77 | HDAC3 (0.49) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL4583278 | 0.75 | HPGD (0.61) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL15662405 | 0.74 | MEN1 (0.60) | MEN1KMT2AMAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430589-A | 2-aminopyrimidine compound or salt thereof, and preparation method and application thereof | 励缔(杭州)医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |