Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC11A2 | P49281 | 3/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30777055 | 1.00 | SLC11A2 (0.43) | SLC11A2GRM7KDM4EALDH1A1HPGD | |
| SCHEMBL30777108 | 0.89 | GRM7 (0.50) | SLC11A2GRM7KDM4EALDH1A1FFAR4 | |
| SCHEMBL29175846 | 0.89 | GRM7 (0.50) | SLC11A2GRM7KDM4EALDH1A1FFAR4 | |
| SCHEMBL30777029 | 0.87 | GRM7 (0.49) | SLC11A2GRM7KDM4EALDH1A1HPGD | |
| SCHEMBL29175817 | 0.87 | GRM7 (0.49) | SLC11A2GRM7KDM4EALDH1A1HPGD | |
| SCHEMBL29175833 | 0.86 | NR3C1 (0.46) | GRM7ALDH1A1FFAR4L3MBTL1 | |
| SCHEMBL30777031 | 0.85 | GRM7 (0.50) | SLC11A2GRM7KDM4EALDH1A1HPGD | |
| SCHEMBL29175756 | 0.85 | GRM7 (0.50) | SLC11A2GRM7KDM4EALDH1A1HPGD | |
| SCHEMBL30777102 | 0.83 | PDE5A (0.45) | GRM7FFAR4L3MBTL1PDCD1CD274 | |
| SCHEMBL29175876 | 0.83 | PDE5A (0.45) | GRM7FFAR4L3MBTL1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117597331-A | Substituted heterobicyclic derivatives as MGLU7 receptor negative allosteric modulators | 阿德克斯法尔马股份公司 | 2024-02-23 | — | — | CN | disclosed |