Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445584 | 1.00 | TSHR (0.44) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL8053585 | 1.00 | TSHR (0.44) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL290865 | 1.00 | TSHR (0.44) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL8379912 | 1.00 | TSHR (0.44) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL292061 | 1.00 | TSHR (0.44) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL8377210 | 1.00 | TSHR (0.44) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL8374781 | 1.00 | TSHR (0.44) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL8378823 | 1.00 | TSHR (0.44) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL292459 | 1.00 | TSHR (0.44) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL204424 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266958-B1 | Antiviral agent | SHIONOGI & CO (JP) | 2017-03-15 | — | — | EP | disclosed |
| US-20170066754-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
| US-9572813-B2 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2017-02-21 | — | — | US | disclosed |
| EP-3042894-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2016-07-13 | — | — | EP | disclosed |
| EP-1142983-B1 | Lubricant additive | IDEMITSU KOSAN CO (JP) | 2016-02-24 | — | — | EP | disclosed |
| EP-1736530-B1 | LUBRICATING OIL COMPOSITION FOR CONTINUOUSLY VARIABLE TRANSMISSION | IDEMITSU KOSAN CO (JP) | 2016-02-03 | — | — | EP | disclosed |
| US-20150202208-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2015-07-23 | — | — | US | disclosed |
| EP-2033952-B1 | Nitrogen-containing Heteroaryl compounds having HIV Integrase Inhibitory Activity | SHIONOGI & CO (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |
| EP-2321319-B1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2012-03-14 | — | — | EP | disclosed |
| US-4435338-A | LUBRICANT ADDITIVES | CIBA-GEIGY CORPORATION (US) | 1984-03-06 | — | — | US | disclosed |
| US-RE31343-E | STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1983-08-09 | — | — | US | disclosed |
| US-RE31342-E | STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1983-08-09 | — | — | US | disclosed |
| EP-0049222-A1 | Dithiophosphates, process for their preparation and their use as lubricant additives | CIBA-GEIGY AG (CH) | 1982-04-07 | — | — | EP | disclosed |
| US-4279761-A | LUBRICANT ADDITIVE | CIBA-GEIGY CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |
| US-4260503-A | EXTREME PRESSURE AND ANTIWEAR AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4244827-A | AS STABILIZING ADDITIVES FOR LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1981-01-13 | — | — | US | disclosed |
| US-4217233-A | Epithio compounds as additives for lubricants | CIBA-GEIGY CORPORATION (US) | 1980-08-12 | — | — | US | disclosed |
| EP-0001631-A1 | Mercaptans on solid carriers and their application in the stabilisation of synthetic thermoplastic materials that contain chlorine | CIBA-GEIGY AG (CH) | 1979-05-02 | — | — | EP | disclosed |
| EP-0001217-A2 | Epithio compounds or mercaptans, and their application in lubricant compositions | CIBA-GEIGY AG (CH) | 1979-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150202208-A1 | ANTIVIRAL AGENT | ZC3HAV1, ZC3HAV1L, CCNI | TSHR 3427/4885THRB 3798/4885HSD17B10 1765/4885 |
| US-20170066754-A1 | ANTIVIRAL AGENT | ZC3HAV1, ZC3HAV1L, CCNI | TSHR 3427/4885THRB 3798/4885HSD17B10 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.