Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KATNA1 | O75449 | 1/20 | 0.80 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MAP3K11 | Q16584 | 5/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.40 |
| ▸ | TUBB | P07437 | 3/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30800000 | 1.00 | KATNA1 (0.80) | KATNA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28478712 | 0.91 | KATNA1 (0.78) | KATNA1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30800072 | 0.89 | KATNA1 (1.00) | KATNA1MAP3K11CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29176296 | 0.89 | KATNA1 (1.00) | KATNA1MAP3K11CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29176303 | 0.79 | KATNA1 (0.82) | KATNA1MAP3K11CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30799984 | 0.79 | KATNA1 (0.82) | KATNA1MAP3K11CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29176274 | 0.79 | KATNA1 (0.80) | KATNA1MAP3K11CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30800011 | 0.79 | KATNA1 (0.80) | KATNA1MAP3K11CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30800023 | 0.76 | KATNA1 (0.64) | KATNA1MAP3K11TUBB4ATUBBTUBA3C | |
| SCHEMBL29176281 | 0.76 | KATNA1 (0.64) | KATNA1MAP3K11TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732584-B | Diaryl substituted fused heterocycle compound and preparation method and application thereof in pharmacy | 复旦大学 | 2024-02-27 | — | — | CN | disclosed |