Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KATNA1 | O75449 | 1/20 | 0.80 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30800011 | 1.00 | KATNA1 (0.80) | KATNA1CSNK2A1CSNK2A2CSNK2BMAPT | |
| SCHEMBL30800072 | 0.89 | KATNA1 (1.00) | KATNA1CSNK2A1CSNK2A2CSNK2BMAPT | |
| SCHEMBL29176296 | 0.89 | KATNA1 (1.00) | KATNA1CSNK2A1CSNK2A2CSNK2BMAPT | |
| SCHEMBL30799984 | 0.88 | KATNA1 (0.82) | KATNA1CSNK2A1CSNK2A2CSNK2BMAPT | |
| SCHEMBL29176303 | 0.88 | KATNA1 (0.82) | KATNA1CSNK2A1CSNK2A2CSNK2BMAPT | |
| SCHEMBL29176271 | 0.83 | KATNA1 (0.73) | KATNA1CSNK2A1CSNK2A2CSNK2BMAPT | |
| SCHEMBL28475487 | 0.80 | KATNA1 (0.51) | KATNA1TP53MAP3K11 | |
| SCHEMBL29176277 | 0.79 | KATNA1 (0.80) | KATNA1CSNK2A1CSNK2A2CSNK2BMAPT | |
| SCHEMBL30800000 | 0.79 | KATNA1 (0.80) | KATNA1CSNK2A1CSNK2A2CSNK2BMAPT | |
| SCHEMBL30800070 | 0.76 | KATNA1 (0.62) | KATNA1CSNK2A1CSNK2A2CSNK2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732584-B | Diaryl substituted fused heterocycle compound and preparation method and application thereof in pharmacy | 复旦大学 | 2024-02-27 | — | — | CN | disclosed |