SCHEMBL29177239

SCHEMBL29177239

CCCOc1ccc(F)c(OC(N)=O)c1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 1/20 0.44
KMT2A Q03164 2/20 0.43
FAAH O00519 8/20 0.43
MCL1 Q07820 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PLK1 P53350 1/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 2/20 0.40
HSD17B10 Q99714 1/20 0.40
HTT P42858 1/20 0.40
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29177241 0.88 KDM4E (0.49) KAT6AMAPTFFAR1FFAR4
SCHEMBL9615380 0.80 CA1 (0.47) KMT2AMEN1MAPT
SCHEMBL29177221 0.77 PARP10 (0.49) KAT6AKMT2AMEN1FFAR4
SCHEMBL29177279 0.77 MAPT (0.40) KMT2AMEN1MAPTHSD17B10HTT
SCHEMBL29177379 0.76 CYP4F2 (0.39) KMT2AMEN1MAPT
SCHEMBL6835721 0.75 KMT2A (0.53) KMT2AL3MBTL1PLK1MEN1MAPT
SCHEMBL1676910 0.75 KAT6A (0.39) KAT6AKMT2AMCL1L3MBTL1MEN1
SCHEMBL29177295 0.75 CYP4F2 (0.55) KMT2AFAAHHTT
SCHEMBL27091691 0.74 PIM1 (0.42) KMT2AFFAR1FFAR4
SCHEMBL2212307 0.73 LTA4H (0.46) KAT6AKMT2AMCL1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117242060-A Isoindolinone compounds 蒙特罗萨医疗公司 2023-12-15 CN disclosed