Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30695916 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNAKCNJ1MAPTSMN1; SMN2 | |
| SCHEMBL29177423 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNAKCNJ1MAPTSMN1; SMN2 | |
| SCHEMBL29739553 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNAKCNJ1MAPTSMN1; SMN2 | |
| SCHEMBL19419599 | 0.83 | ALDH1A1 (0.69) | ALDH1A1LMNAKCNJ1MAPTSMN1; SMN2 | |
| SCHEMBL922222 | 0.81 | KCNJ1 (0.57) | ALDH1A1LMNAKCNJ1MAPTSMN1; SMN2 | |
| SCHEMBL30697195 | 0.81 | KCNJ1 (0.57) | ALDH1A1LMNAKCNJ1MAPTSMN1; SMN2 | |
| SCHEMBL29177214 | 0.81 | KDM4E (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL30695907 | 0.81 | KDM4E (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL27292140 | 0.78 | KCNH2 (0.47) | ALDH1A1MAPTSMN1; SMN2ABL1KCNH2 | |
| SCHEMBL29947806 | 0.77 | ALDH1A1 (0.65) | ALDH1A1LMNAKCNJ1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |